Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006537, PubMed:31006538).
规格
产品名称
Recombinant Human MAP1LC3A Protein
别名
重组人MAP1LC3A蛋白 | 重组人 MAP1LC3A 蛋白
英文别名
Autophagy related protein LC3 A | ATG8E | Autophagy related ubiquitin like modifier LC3 A | Autophagy-related protein LC3 A | Autophagy-related ubiquitin-like modifier LC3 A | LC3 | LC3A | MAP1 light chain 3 like protein 1 | MAP1 light chain 3-like protei
Recombinant Human MAP1LC3A Protein (rp183742) - SDS-PAGE 3 μg/lane of Recombinant Human MAP1LC3A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 13.1 kDa under reducing conditions and 13.1 & 30.6 kDa under non-reducing conditions.
ZJ24F0809713
危险品化学品经营许可证（带存储）