Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
规格
产品名称
Recombinant Human Profilin 1 Protein
别名
重组人Profilin 1蛋白 | 重组人类 Profilin 1 蛋白
英文别名
Actin binding protein | ALS18 | Epididymis tissue protein Li 184a | OTTHUMP00000125244 | Pfn | PFN 1 | PFN1 | PROF1_HUMAN | Profilin I | Profilin-1 | Profilin1 | ProfilinI
13.8 kDa, under reducing conditions; 13.8 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 20mM Tris, 500mM NaCl, 50mM Imidazole, pH8.0
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可稳定保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human Profilin 1 Protein (rp183752) - SDS-PAGE 2 μg/lane of Recombinant Human Profilin 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 13.8 kDa.