KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
规格
产品名称
Recombinant Human KIR2DL4/CD158d Protein
别名
重组人KIR2DL4/CD158d蛋白 | 重组人杀伤细胞免疫球蛋白样受体2DL4蛋白蛋白
英文别名
103AS | CD158 antigen-like family member D | CD158d antigen | CD158d | CD158DKIR103ASKiller cell inhibitory receptor 103AS | G9P | killer cell immunoglobulin-like receptor 2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 6个月；复溶后建议分装，避免反复冻融。
图片
Recombinant Human KIR2DL4/CD158d Protein (rp184053) - SDS-PAGE 3 μg/lane of Recombinant Human KIR2DL4/CD158d Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 59.0 kDa.
危险品化学品经营许可证（带存储）