Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. The ED50 for this effect is 1.06 μg/mL.
LAIR-2(白细胞相关 Ig 样受体-2;CD306)是一种 131 个氨基酸(aa)的分泌型蛋白质,含有一个 Ig 样 C2 型结构域,是 Ig 超家族的成员。与 LAIR-1(其跨膜对应物)相比,它在信号序列和细胞外结构域上有 83% 的氨基酸相同度;虽然一个是分泌型,一个是膜结合型,但这两种 LAIR 蛋白被认为来自一个共同的基因祖先,而且似乎具有相似的粘附特性。这表明 LAIR-2 可能与 LAIR-1 竞争配体结合。LAIR-2 的另一种 114 aa 的剪接形式在 C 端截短,但保留了整个 Ig 结构域。这些剪接形式的表达情况以及在其他物种中是否存在同源物尚未见报道。
生物活性
Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. The ED50 for this effect is 1.06 μg/mL.
15.7-19.8 kDa, under reducing conditions; 15.7-19.8 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human LAIR2 Protein (rp184062) - Protein Bioactivity Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. The ED₅₀ for this effect is 1.06 μg/mL.
Recombinant Human LAIR2 Protein (rp184062) - SDS-PAGE 3 μg/lane of Recombinant Human LAIR2 Protein Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15.7-19.8 kDa.