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224,000+ 科研产品 · 三重ISO认证 · 每个产品均提供COA和SDS · 现货产品当日发货

Recombinant Human VE-Cadherin Protein

货号: rp184119
COA
有货
级别和纯度: 无动物源 ? 无动物源（Animal Free）—— 不含动物源成分生产，降低污染风险。适用于避免动物源材料的生物制造和培养。 无载体 ? 无载体（Carrier Free）—— 不含添加的载体蛋白/稳定剂。当载体（如 BSA）会干扰偶联或敏感检测时使用。 生物活性 ? 生物活性级（Bioactive）—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。 ActiBioPure™ ? ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。 高性能 ? 高性能级 —— 纯度和性能特性经过优化。适用于普通等级无法满足的灵敏分析。 His标签 ? 组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白，供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。 PBS Only ? 仅 PBS 配方 —— 以磷酸盐缓冲液供应，不含其他添加剂。当需要不含稳定剂/载体的洁净 PBS 缓冲液时使用。 ≥90%(SDS-PAGE)
Accession #
P33151
蛋白标签
C-His
表达系统
HEK293
内毒素水平
<1.0 EU/μg
生物活性
Measured by the ability of the immobilized protein to support the adhesion of HUVEC cells. The ED50 for this effect is 308.4ng/mL. Measured by the ability of the immobilized protein to support the adhesion of HUVEC human umbilical vein endothelial cells, When 3 x 104 cells per well are added to Recombinant Human VE-Cadherin Protein (rp184119) coated plates (370 ng/mL, 100 μL/well) can significantly improve cells adhesion.
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规格
库存
价格
数量
10μg
rp184119-10μg
现货 Stock Image
¥799.90
50μg
rp184119-50μg
现货 Stock Image
¥2,299.90
100μg
rp184119-100μg
现货 Stock Image
¥3,669.90
1mg
rp184119-1mg
期货 Stock Image
¥16,999.90
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大包装 / 定制
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SDS
安全数据
COA
分析证书
Data Sheet
产品数据
Spec Sheet
规格说明
大包装询价 收藏夹
Recombinant Human VE-Cadherin Protein
概述 规格 储存与运输 图片 技术文档 高级数据 质检证书（CoA,COO,BSE/TSE 和分析图谱) 溶液计算器
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为什么选择此级别

ActiBioPure™,His标签,PBS Only,无动物源,无载体,生物活性,高性能 级 提供 ≥90%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

🌡

储存与运输

-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。

📋

质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

📚

文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

概述


Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.

规格

产品名称
Recombinant Human VE-Cadherin Protein
别名
重组人VE-Cadherin蛋白 | 重组人VE-钙粘蛋白
英文别名
7B4 | 7B4 antigen | cadherin 5, type 2 (vascular endothelium) | cadherin 5, type 2, VE-cadherin (vascular epithelium) | Cadherin-5 | CD144 antigen | CD144 | CDH5 | endothelial-specific cadherin | FLJ17376 | Vascular endothelial cadherin | VECadherin | VE-
规格或纯度
无动物源, 无载体, 生物活性, ActiBioPure™, 高性能, His标签, PBS Only, ≥90%(SDS-PAGE)
生物活性
Measured by the ability of the immobilized protein to support the adhesion of HUVEC cells. The ED50 for this effect is 308.4ng/mL. Measured by the ability of the immobilized protein to support the adhesion of HUVEC human umbilical vein endothelial cells, When 3 x 104 cells per well are added to Recombinant Human VE-Cadherin Protein (rp184119) coated plates (370 ng/mL, 100 μL/well) can significantly improve cells adhesion.
表达系统
HEK293
种属
人(Human)
氨基酸
1-593 aa
序列
MQRLMMLLATSGACLGLLAVAAVAAAGANPAQRDTHSLLPTHRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNAKYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQKKPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTKKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFILNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQHHHHHH
蛋白标签
C-His
无载体
Yes
无动物源
Yes
来源
重组表达
预测分子量
67.5 kDa
SDS-PAGE
82.0-98.0 kDa, under reducing conditions; 82.0-98.0 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片

Recombinant Human VE-Cadherin Protein (rp184119) - Protein Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of HUVEC cells. The ED50 for this effect is 308.4 ng/mL.

Recombinant Human VE-Cadherin Protein (rp184119) - Protein Bioactivity
Measured by the ability of the immobilized protein to support the adhesion of HUVEC human umbilical vein endothelial cells, When 3 x 104 cells per well are added to Recombinant Human VE-Cadherin Protein (rp184119) coated plates (370 ng/mL, 100 μL/well) can significantly improve cells adhesion.

Recombinant Human VE-Cadherin Protein (rp184119) - SDS-PAGE
3 μg/lane of Recombinant Human VE-Cadherin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 82.0-98.0 kDa.

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number) 证书类型 货号
ZJ25F1028365 分析证书 rp184119
ZJ25F1028366 分析证书 rp184119
ZJ25F1028367 分析证书 rp184119
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