Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
规格
产品名称
Recombinant Human AMPK alpha 1 Protein
别名
重组人AMPK alpha 1蛋白 | 重组人类 AMPK alpha 1 蛋白
英文别名
5 AMP activated protein kinase alpha 1catalytic subunit | 5 AMP activated protein kinase catalytic alpha 1 chain | 5' AMP activated protein kinase catalytic subunit alpha 1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | AAPK1 | AAPK1_HUMAN
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human AMPK alpha 1 Protein (rp184863) - SDS-PAGE 3 μg/lane of Recombinant Human AMPK alpha 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 28.8 & 54.8 kDa under reducing conditions and 29.6 & 54.5 kDa under non-reducing conditions.
ZJ24F0809872
危险品化学品经营许可证（带存储）