baculoviral IAP repeat containing 7 | baculoviral IAP repeat-containing 7 | BIRC7 | KIAP | KIAPRING finger protein 50 | Kidney inhibitor of apoptosis protein | livin inhibitor-of-apoptosis | Livin | Melanoma inhibitor of apoptosis protein | ML-IAP | MLIAP
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy.
Post-translational: Autoubiquitinated and undergoes proteasome-mediated degradation. The truncated protein (tLivin) not only loses its anti-apoptotic effect but also acquires a pro-apoptotic effect.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human Livin Protein (rp184877) - SDS-PAGE 2 μg/lane of Recombinant Human Livin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 37.4 kDa.
ZJ24F1215440
危险品化学品经营许可证（带存储）