| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp186538-100μg |
100μg |
现货  |
| |
| rp186538-1mg |
1mg |
期货 |
| |
| rp186538-5mg |
5mg |
期货 |
|
| 产品名称 | Recombinant Rat Leptin Protein |
|---|---|
| 别名 | 重组大鼠瘦素蛋白 | 重组人大鼠Leptin蛋白 |
| 英文别名 | FLJ94114 | LEP | leptin (murine obesity homolog) | leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | obese, mouse, homolog of | Obesity factor | OBOBS |
| 规格或纯度 | 无载体, ≥95%(SDS-PAGE) |
| 生化机理 | Leptin is an identified protein product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of Leptin have been found to be obese and diabetic and to have reduced activity, metabolism, and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse, and rat cells. Rat Leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. Rat Leptin cDNA encodes a 167 amino acid residue protein with a 21 amino acid residue signal sequence that is cleaved to yield the 146 amino acid residue mature protein. The expression of Leptin mRNA has been shown to be restricted to adipose tissue. A high-affinity receptor for Leptin (OB-R) with homology to gp130 and the G-CSF receptor has been cloned. OB-R mRNA has been shown to be expressed in the choroid plexus and in the hypothalamus. OB-R has also been identified as an isoform of B219, a sequence that is expressed in at least four isoforms in very primitive hematopoietic cell populations and in a variety of lymphohematopoietic cell lines. The possible roles of Leptin in body weight regulation, hematopoiesis and reproduction are being investigated. |
| 生物活性 | Testing in progress |
| 内毒素水平 | <1.0 EU/μg |
| 表达系统 | E. coli |
| 种属 | 大鼠(Rat) |
| 氨基酸 | 22-167 aa |
| 序列 | VPIHKVQDDTKTLIKTIVTRINDISHTQSVSARQRVTGLDFIPGLHPILSLSKMDQTLAVYQQILTSLPSQNVLQIAHDLENLRDLLHLLAFSKSCSLPQTRGLQKPESLDGVLEASLYSTEVVALSRLQGSLQDILQQLDLSPEC |
| 蛋白标签 | No tag |
| 无载体 | Yes |
| 无动物源 | No |
| Accession # | P50596 |
| 来源 | 重组表达 |
| 预测分子量 | 29.8 kDa |
| SDS-PAGE | 12.7 kDa, under reducing conditions; 12.3 & 29.2 kDa, under non-reducing conditions. |
Recombinant Rat Leptin Protein (rp186538) - SDS-PAGE
3 μg/lane of Recombinant Rat Leptin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 12.7 kDa under reducing conditions and 12.3 & 29.2 kDa under non-reducing conditions.
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from PBS, pH 7.4 |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | Store at -20°C for 1 year. Avoid freeze/thaw cycle. |
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ25F0218468 |
分析证书 | 25-02-28 | rp186538 |
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