Matriptase, a mouse type II membrane serine protease encoded by the ST14 (suppression of tumorigenicity 14) gene, is also known as epithin, and membrane-type serine protease 1/MT-SP1. Its human ortholog MT-SP1/Matriptase (Catalog # 3946-SE), which shares 81% amino acid identity with epithin, has been thought to play an important role in tumor biology and is a potential target for anti-cancer therapy. Matriptase has a multidomain structure containing a putative N-terminal transmembrane region, two CUB domains, four LDLRA repeats, and a C-terminal serine protease domain. The protease domain of epithin starts with Val615. R&D Systems recombinant mouse Matriptase is an active protease and consists of the catalytic domain (Val615 to Val855) and a short peptide (Gly596 to Arg614).
5.0 & 26.6 kDa, under reducing conditions; 5.0 & 26.1 & 27.6 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mMTris, 20% Glycerol, pH 8.0
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Mouse Matriptase/ST14 Catalytic Domain Protein (rp186543) - SDS-PAGE 3 μg/lane of Recombinant Mouse Matriptase/ST14 Catalytic Domain Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 5.0 & 26.6 kDa under reducing conditions and 5.0 & 26.1 & 27.6 kDa under non-reducing conditions. The protein shows features for chain, modified residue, modified residue (large scale data), glycosylation, disulfide bond (UniProt:P56677).
Recombinant Mouse Matriptase/ST14 Catalytic Domain Protein (rp186543) - SDS-PAGE 3 μg/lane of Recombinant Mouse Matriptase/ST14 Catalytic Domain Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 5.0 & 26.6 kDa under reducing conditions and 5.0 & 26.1 & 27.6 kDa under non-reducing conditions. The protein shows features for chain, modified residue, modified residue (large scale data), glycosylation, disulfide bond (UniProt:P56677).