ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.
生物活性
Immobilized Recombinant Human Integrin beta 1 Protein (rp186545) at 1.0 μg/mL can bind OS2966 (anti-ITGB1) (Ab177919) with the EC50 of 36.5 ng/mL.
108.0-132.9 kDa, under reducing conditions; 103.1-124.2 & 143.8-250.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human Integrin beta 1 Protein (rp186545) - ELISA Immobilized Recombinant Human Integrin beta 1 Protein (rp186545) at 1.0 μg/mL can bind OS2966 (anti-ITGB1) (Ab177919) with the EC50 of 36.5 ng/mL.
Recombinant Human Integrin beta 1 Protein (rp186545) - SDS-PAGE 3 μg/lane of Recombinant Human Integrin beta 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 108.0-132.9 kDa under reducing conditions and 103.1-124.2 & 143.8-250.0 kDa under non-reducing conditions.