endoplasmic reticulum protein 44 | endoplasmic reticulum resident protein 44 kDa | ER protein 44 | ERp44 | KIAA0573endoplasmic reticulum resident protein 44 | PDIA10 | protein disulfide isomerase family A | member 10 | thioredoxin domain containing 4 (end
规格或纯度
无动物源, 无载体, His标签, ≥85%(SDS-PAGE), expressed in HEK293; 见COA
生化机理
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif (PubMed:11847130, PubMed:14517240).
Inhibits the calcium channel activity of ITPR1 (PubMed:15652484).
May have a role in the control of oxidative protein folding in the endoplasmic reticulum (PubMed:11847130, PubMed:14517240, PubMed:29858230).
Required to retain ERO1A and ERO1B in the endoplasmic reticulum (PubMed:11847130, PubMed:29858230).
44.0 kDa, under reducing conditions; 42.3 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
浓度
expressed in HEK293; 见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 12个月；复溶后建议分装，避免反复冻融。
图片
Recombinant Human TXNDC4 Protein (rp188248) - SDS-PAGE
3 μg/lane of Recombinant Human TXNDC4 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 44.0 kDa under reducing conditions and 42.3 kDa under non-reducing conditions.
There are multiple pairs of disulfide bonds in the protein sequence. Disulfide bonds may cause the protein to present as a polymer in a non-reducing conditions (Uniprot ID: Q9BS26).
ZJ26F0738108
危险品化学品经营许可证（带存储）