Immobilized Recombinant Human Peroxiredoxin 5/PRDX5 Protein (rp188268) at 1.0 μg/mL can bind Recombinant Peroxiredoxin 5 Antibody (Ab121338) with the EC50 of 3.4 ng/mL.
ACR1 Protein, Human | AOEB166 Protein, Human | B166 Protein, Human | HEL-S-55 Protein, Human | MGC117264 Protein, Human | MGC142283 Protein, Human | MGC142285 Protein, Human | PLP Protein, Human | PMP20 Protein, Human | PRDX6 Protein, Human | prx-V Protei
Peroxiredoxin-5, also known as Alu corepressor 1, Antioxidant enzyme B166, Liver tissue 2D-page spot 71B, Peroxisomal antioxidant enzyme, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5 and ACR1, is cytoplasm protein that belongs to the peroxiredoxin 2 family. Peroxiredoxin-5 / PRDX5 reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-5 / PRDX5 is involved in intracellular redox signaling. The Peroxiredoxins / Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Post-translational: S-palmitoylated (PubMed:31740833). Palmitoylation occurs on the active site, inhibiting its reactivity; therefore PRDX5 palmitoylation status determines its antioxidant capacity (PubMed:31740833). Isoform Mitochondrial, S-palmitoylated (PubMed:31740833). Depalmitoylated by ABHD10 (PubMed:31740833).
生物活性
Immobilized Recombinant Human Peroxiredoxin 5/PRDX5 Protein (rp188268) at 1.0 μg/mL can bind Recombinant Peroxiredoxin 5 Antibody (Ab121338) with the EC50 of 3.4 ng/mL.
15.2 kDa, under reducing conditions; 14.9 & 16.2 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human Peroxiredoxin 5/PRDX5 Protein (rp188268) - ELISA Immobilized Recombinant Human Peroxiredoxin 5/PRDX5 Protein (rp188268) at 1.0 μg/mL can bind Recombinant Peroxiredoxin 5 Antibody (Ab121338) with the EC₅₀ of 3.4 ng/mL.
Recombinant Human Peroxiredoxin 5/PRDX5 Protein (rp188268) - SDS-PAGE 3 μg/lane of Recombinant Human Peroxiredoxin 5/PRDX5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15.2 kDa under reducing conditions and 14.9 & 16.2 kDa under non-reducing conditions.
ZJ24F1215611
危险品化学品经营许可证（带存储）