Recombinant Human S100A1 Protein

货号: rp188279
有货
级别和纯度: 无载体 ? 无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。 生物活性 ? 生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。 ActiBioPure™ ? ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。 PBS Only ? 仅 PBS 配方 —— 以磷酸盐缓冲液供应,不含其他添加剂。当需要不含稳定剂/载体的洁净 PBS 缓冲液时使用。 ≥95%(SDS-PAGE) 见COA
Accession #
P23297
蛋白标签
No tag
表达系统
E. coli
内毒素水平
<1.0 EU/μg
生物活性
Immobilized Recombinant Human S100A1 Protein (rp188279) at 5.0 μg/mL can bind Recombinant Human S100B Protein (rp188279) with a linear range of 0.0007-0.56 μg/mL.
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规格
库存
价格
数量
10μg
rp188279-10μg
现货 Stock Image
¥799.90
50μg
rp188279-50μg
现货 Stock Image
¥2,299.90
100μg
rp188279-100μg
现货 Stock Image
¥3,679.90
1mg
rp188279-1mg
期货 Stock Image
¥18,999.90
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为什么选择此级别

ActiBioPure™,PBS Only,无载体,生物活性 级 提供 ≥95%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

规格

产品名称
Recombinant Human S100A1 Protein
别名
重组人S100A1蛋白 | 重组人S100钙结合蛋白A1蛋白
英文别名
protein S100-A1 | S100 alpha | S100 calcium binding protein A1 | S100 calcium-binding protein A1S100 | S-100 protein alpha chain | S-100 protein subunit alpha | S100 protein | alpha polypeptide | S100A | S100A1 | S100-alpha
规格或纯度
无载体,生物活性,ActiBioPure™,PBS Only,≥95%(SDS-PAGE),见COA
生化机理
S100A1 is a Ca2+ binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies. Post-translational: Glutathionylated; glutathionylation increases affinity to calcium about 10-fold.
生物活性
Immobilized Recombinant Human S100A1 Protein (rp188279) at 5.0 μg/mL can bind Recombinant Human S100B Protein (rp188279) with a linear range of 0.0007-0.56 μg/mL.
表达系统
E. coli
种属
人(Human)
氨基酸
2-94 aa
序列
GSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS​
蛋白标签
No tag
无载体
Yes
无动物源
No
来源
重组表达
预测分子量
10.4 kDa
SDS-PAGE
10.0 kDa, under reducing conditions; 10.0 & 20.9 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 12个月;复溶后建议分装,避免反复冻融。
图片

Recombinant Human S100A1 Protein (rp188279) - Binding Activity
Immobilized Recombinant Human S100A1 Protein (rp188279) at 5.0 μg/mL can bind Recombinant Human S100B Protein (rp155671) with a linear range of 0.7-560 ng/mL.

Recombinant Human S100A1 Protein (rp188279) - SDS-PAGE
3 μg/lane of Recombinant Human S100A1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 10.0 kDa under reducing conditions and 10.0 & 20.9 kDa under non-reducing conditions.
Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain (PubMed: 21296671).

技术文档

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✅ 分析证书 (COA)

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高级数据

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ25F0825570 分析证书 rp188279
ZJ25F0825571 分析证书 rp188279
ZJ25F0825572 分析证书 rp188279
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