Recombinant Human Cdc37 Protein

货号: rp188343
有货
级别和纯度: 无载体 ? 无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。 生物活性 ? 生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。 ActiBioPure™ ? ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。 His标签 ? 组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。 PBS Only ? 仅 PBS 配方 —— 以磷酸盐缓冲液供应,不含其他添加剂。当需要不含稳定剂/载体的洁净 PBS 缓冲液时使用。 ≥90%(SDS-PAGE) 见COA
Accession #
Q16543
蛋白标签
N-His
表达系统
E. coli
内毒素水平
<1.0 EU/μg
生物活性
Immobilized Recombinant Human Cdc37 Protein (rp188343) at 1.0 μg/mL can bind Recombinant Cdc37 Antibody (Ab095626) with the EC50 of 2.5 ng/mL.
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规格
库存
价格
数量
10μg
rp188343-10μg
期货 Stock Image
¥1,299.90
50μg
rp188343-50μg
期货 Stock Image
¥3,669.90
100μg
rp188343-100μg
期货 Stock Image
¥5,879.90
1mg
rp188343-1mg
期货 Stock Image
¥29,999.90
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为什么选择此级别

ActiBioPure™,His标签,PBS Only,无载体,生物活性 级 提供 ≥90%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

规格

产品名称
Recombinant Human Cdc37 Protein
别名
重组人Cdc37蛋白 | 重组人细胞分裂周期37, HSP90辅伴侣蛋白
英文别名
CDC 37 | Cdc37 | CDC37 cell division cycle 37 homolog | CDC37 cell division cycle 37 S cerevisiae homolog | CDC37 cell division cycle 37, S cerevisiae, homolog of | Cdc37 homolog | CDC37 protein | CDC37_HUMAN | CDC37A | cell division cycle 37 | Cell divis
规格或纯度
无载体,生物活性,ActiBioPure™,His标签,PBS Only,≥90%(SDS-PAGE),见COA
生化机理
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is thought to play an important role in the establishment of signaling pathways controlling cell proliferation through targeting intrinsically unstable oncoprotein kinases such as Cdk-4, Raf-1, and src to the molecular chaperone Hsp90. Decreased Hsp90 expression can reduce the levels of microtubule-associated protein tau, whose overexpression may induce many diseases. CDC37 is considered as a co-chaperone that is classified as Hsp90's accessory proteins. It has been reported that suppression of Cdc37 destabilized tau, leading to its clearance, whereas cdc37 overexpression preserved tau.Cdc37 was found to co-localize with tau in neuronal cells and to physically interact with tau from human brain. Moreover, Cdc37 levels significantly increased with age. Post-translational: Constitutively sumoylated by UBE2I.
生物活性
Immobilized Recombinant Human Cdc37 Protein (rp188343) at 1.0 μg/mL can bind Recombinant Cdc37 Antibody (Ab095626) with the EC50 of 2.5 ng/mL.
表达系统
E. coli
种属
人(Human)
氨基酸
2-378 aa
序列
MHHHHHHVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
蛋白标签
N-His
无载体
Yes
无动物源
No
来源
重组表达
预测分子量
45.3 kDa
SDS-PAGE
45.0 kDa, under reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4.
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20℃ for 6 months. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片

Recombinant Human Cdc37 Protein (rp188343) - ELISA
Immobilized Recombinant Human Cdc37 Protein (rp188343) at 1.0 μg/mL can bind Recombinant Cdc37 Antibody (Ab095626) with the EC50 of 2.5 ng/mL.

Recombinant Human Cdc37 Protein (rp188343) - SDS-PAGE
3 μg/lane of Recombinant Human Cdc37 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 45.0 kDa.

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

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🔬 规格说明书

该级别的完整质量属性和验收标准。

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高级数据

质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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溶液计算器