级别和纯度: 无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。生物活性?生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。ActiBioPure™?ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。≥95%(SDS-PAGE)See COA
Accession #
P42773
蛋白标签
N-His
表达系统
E. coli
内毒素水平
<1.0 EU/μg
生物活性
Immobilized Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) at 2.0 μg/mL can bind Recombinant p18 INK4c/CDKN2C Antibody (Ab119609) with the EC50 of 6.68 ng/mL.
无载体,生物活性,ActiBioPure™,His标签,≥95%(SDS-PAGE),See COA
生化机理
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.
生物活性
Immobilized Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) at 2.0 μg/mL can bind Recombinant p18 INK4c/CDKN2C Antibody (Ab119609) with the EC50 of 6.68 ng/mL.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) - ELISA Immobilized Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) at 2.0 μg/mL can bind Recombinant p18 INK4c/CDKN2C Antibody (Ab119609) with the EC₅₀ of 6.68 ng/mL.
Recombinant Human p18 INK4c/CDKN2C Protein (rp188348) - SDS-PAGE 3 μg/lane of Recombinant Human p18 INK4c/CDKN2C Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 16.5 kDa.