Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Post-translational: Phosphorylated and activated in vitro upon phosphorylation at Ser-74 by CSNK1D/CK1.
29.3 & 62.5 kDa, under reducing conditions; 29.3 & 62.5 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
PBS, 50% Glycerol, 1mM TCEP, pH 7.4
浓度
COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20℃ for 6 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Human DCK Protein (rp188368) - SDS-PAGE 3 μg/lane of Recombinant Human DCK Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.3 & 62.5 kDa. DCK is a homodimeric globular protein (PMID: 12808445).