CDA03 | dCTP pyrophosphatase 1 | DCTP1_HUMAN | dCTPase 1 | DCTPP1 | Deoxycytidine triphosphatase 1 | Deoxycytidine-triphosphatase 1 | RS21C6 | XTP3 transactivated gene A protein | XTP3 transactivated protein A | XTP3-transactivated gene A protein
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. It may protect DNA or RNA against the incorporation of non-canonical nucleotide triphosphates. DCTPP1 may also protect cells against inappropriate methylation of CpG islands by DNA methyltransferases.
19.1 kDa, under reducing conditions; 20.0 & 37.1 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 100mM NaCl, 10% Glycerol, pH 8.0
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human XTP3TPA Protein (rp188369) - SDS-PAGE 3 μg/lane of Recombinant Human XTP3TPA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 19.1 kDa under reducing conditions and 20.0 & 37.1 kDa under non-reducing conditions.