BAG9 | Cancer associated surface antigen | Cancer associated surface antigen RCAS1 | Cancer-associated surface antigen RCAS1 | EB9 | EBAG 9 | EBAG9 | Estrogen receptor binding fragment associated gene 9 protein | Estrogen receptor binding site associated
规格或纯度
无载体,生物活性,ActiBioPure™,His标签,≥90%(SDS-PAGE),See COA
生化机理
RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
生物活性
Immobilized Recombinant Human RCAS1 Protein (rp188379) at 1.0 μg/mL can bind RCAS1 Mouse mAb (Ab124859) with the EC50 of 33.9 ng/mL.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human RCAS1/EBAG9 Protein (rp188379) - ELISA Immobilized Recombinant Human RCAS1/EBAG9 Protein (rp188379) at 1.0 μg/mL can bind RCAS1 Mouse mAb (Ab124859) with the EC₅₀ of 33.9 ng/mL.
Recombinant Human RCAS1/EBAG9 Protein (rp188379) - SDS-PAGE 2 μg/lane of Recombinant Human RCAS1/EBAG9 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 30.7 kDa.