Immobilized Recombinant Human Proteasome 20S Alpha 2/HC3 Protein (rp188416) at 1.0 μg/mL can bind Recombinant Proteasome 20S alpha 2/HC3 Antibody (Ab123373) with the EC50 of 36.4 ng/mL.
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.
Post-translational: Phosphorylated on tyrosine residues; which may be important for nuclear import.
生物活性
Immobilized Recombinant Human Proteasome 20S Alpha 2/HC3 Protein (rp188416) at 1.0 μg/mL can bind Recombinant Proteasome 20S alpha 2/HC3 Antibody (Ab123373) with the EC50 of 36.4 ng/mL.
Store at -20℃ for 6 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
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Recombinant Human Proteasome 20S Alpha 2/HC3 Protein (rp188416) - ELISA Immobilized Recombinant Human Proteasome 20S Alpha 2/HC3 Protein (rp188416) at 1.0 μg/mL can bind Recombinant Proteasome 20S alpha 2/HC3 Antibody (Ab123373) with the EC₅₀ of 36.4 ng/mL.
Recombinant Human Proteasome 20S Alpha 2/HC3 Protein (rp188416) - SDS-PAGE 3 μg/lane of Recombinant Human Proteasome 20S Alpha 2/HC3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 24.8 & 45.9 & 85.3 kDa. Proteasome 20S Alpha 2/HC3 (PSMA2) tends to form multimers when expressed alone. This is primarily due to the lack of necessary chaperones and interactions with other subunits, which may prevent its proper folding and assembly (PMID: 22930756).
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