无动物源,无载体,His标签,≥90%(SDS-PAGE),expressed in HEK293, 见 COA
生化机理
SSc5D (Soluble Scavenger with 5 Domains) is a member of scavenger receptor cysteine-rich (SRCR) superfamily that comprises a group of proteins with one or more domains sharing structural homology with the membrane distal extracellular domain of the macrophage type I scavenger receptor. Mature human SSc5D consists of 1573 amino acids (aa), including five SRCR domains at the N-terminus and a heavily glycosylated, mucin-like domain at the C-terminus. Within N‑terminal SRCR domains, human SSc5D shares 95% and 96% aa sequence identity with mouse and rat SSc5D, respectively. SSc5D is produced by monocyte/macrophages, T cells and several epithelial cells from placenta, spleen, and colon. Many members of the SRCR super family bind to and clear bacteria, fungi or viruses from infected host. SSc5D physically interacts with whole bacteria cells especially to E. coli strains. These findings can help fight bacterial infections by discriminating between different bacteria strains and species.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 12个月;复溶后建议分装,避免反复冻融。
图片
Recombinant Human SSc5D Protein (rp188474) - SDS-PAGE
2 μg/lane of Recombinant Human SSc5D Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 131.2-187.9 kDa under reducing conditions.