CacyBP | Calcyclin binding protein | Calcyclin-binding protein | CYBP_HUMAN | GIG 5 | GIG5 | Growth inhibiting gene 5 | Growth inhibiting gene 5 protein | hCacyBP | MGC87971 | PNAS 107 | PNAS107 | RP1 102G20.6 | S100A6 binding protein | S100A6-binding pro
规格或纯度
无载体, His标签, ≥80%(SDS-PAGE), 见COA
生化机理
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
Post-translational: Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations.
23.1 kDa, under reducing conditions; 23.5 & 22.3 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 20mM Tris, 100mM NaCl, 1mM DTT, pH 8.0
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human CacyBP Protein (rp189282) - SDS-PAGE 2 μg/lane of Recombinant Human CacyBP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 23.1 kDa under reducing conditions and 23.5 & 22.3 kDa under non-reducing conditions. CacyBP can form homodimers, and the two bands observed under non-reducing conditions likely represent two different conformations (Uniprot: Q9HB71).