Calcineurin B homolog | Calcineurin B homologous protein | Calcineurin homologous protein | Calcineurin like EF hand protein 1 | Calcium binding protein CHP | Calcium binding protein p22 | Calcium-binding protein CHP | Calcium-binding protein p22 | Chp |
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),见COA
生化机理
Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
Post-translational: Phosphorylated; decreased phosphorylation is associated with an increase in SLC9A1/NHE1 Na+/H+ exchange activity. Phosphorylation occurs in serum-dependent manner. The phosphorylation state may regulate the binding to SLC9A1/NHE1. Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic (By similarity). N-myristoylation is required for its association with microtubules and interaction with GAPDH, but not for the constitutive association to membranes.
24.0 kDa, under reducing conditions; 24.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 10% Glycerol, pH 7.5
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃（12个月）；收货后建议分装，避免反复冻融。
图片
Recombinant Human CHP1 Protein (rp189319) - SDS-PAGE 3 μg/lane of Recombinant Human CHP1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 24.0 kDa under reducing conditions and non-reducing conditions.
ZJ25F0927416
危险品化学品经营许可证（带存储）