CAF40 | CCR4-NOT transcription complex subunit 9 | Cell differentiation protein RCD1 homolog | CNOT9 | CT129 | Homo sapiens protein involved in sexual development complete cds | Rcd 1 | Rcd-1 | RCD1 | Rcd1 (required for cell differentiation, S.pombe) homo
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),见COA
生化机理
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
28.8 kDa, under reducing conditions; 28.8 & 31.2 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 20mM Tris, 100M NaCl, 1mM DTT, pH 8.0
浓度
见COA
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human RQCD1 Protein (rp189324) - SDS-PAGE 3 μg/lane of Recombinant Human RQCD1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 28.8 kDa under reducing conditions and 28.8 & 31.2 under non-reducing conditions.