无载体,生物活性,ActiBioPure™,His标签,≥95%(SDS-PAGE),See COA
生化机理
Crk-like protein (CRKL) is a protein kinase containing SH2 and SH3 (src homology) domains which activates the RAS and JUN kinase signaling pathways and transforms fibroblasts in a RAS-dependent manner. CRKL is a substitute of the BCR-ABL tyrosine kinase, it also has a role in fibroblast transformation by BCR-ABL, and has oncogenic potential. May mediate the transduction of intracellular signals.
生物活性
Immobilized Recombinant Human CrkL Protein (rp189337) at 1.0 μg/mL can bind Recombinant CrkL Antibody (Ab097773) with the EC50 of 22.9 ng/mL.
Immobilized Recombinant Human CrkL Protein (rp189337) at 1.0 μg/mL can bind Recombinant CrkL Antibody (Ab097773) with the EC₅₀ of 22.9 ng/mL.
Recombinant Human CrkL Protein (rp189337) - SDS-PAGE
3 μg/lane of Recombinant Human CrkL Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 36.4 kDa under reducing conditions and non-reducing conditions.