级别和纯度: 无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。≥90%(SDS-PAGE)expressed in E. coli; 见COA
CTD small phosphatase-like protein | CTDSP-like | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3 | NIF-like protein | Nuclear LIM interactor-interacting factor 1 | NLI-interacting factor 1 | Protein YA22 | hYA22 | RBSP
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),expressed in E. coli; 见COA
生化机理
CTD small phosphatase-like protein (CTDSPL) specially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the biggest RNA polymerase II subunit POLR2A. CTDSPL negatively regulates RNA polymerase II transcription, probably by directing the transition from initiation/capping to processive transcript elongation. CTDSPL is employed by REST to neuronal genes which contain RE-1 elements, directing to neuronal gene silencing in non-neuronal cells.
Recombinant Human CTDSPL Protein (rp189355) - SDS-PAGE
3 μg/lane of Recombinant Human CTDSPL Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 19.0 kDa.