级别和纯度: 无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。≥95%(SDS-PAGE)expressed in E. coli; 见COA
ARF Nucleotide-Binding Site Opener | Pleckstrin Homology Sec7 And Coiled-Coil Domains 2 (Cytohesin-2) | PH SEC7 And Coiled-Coil Domain-Containing Protein 2 | Cytohesin 2 | Protein ARNO | ARF Exchange Factor | Sec7p-Like | PSCD2 | PSCD2L | CTS18.1
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),expressed in E. coli; 见COA
生化机理
Cytohesin 2 (CYTH2) is an ARF-1 guanine nucleotide exchange factor (GEF). ARF (ADP ribosylation factor) proteins are a part of a group within the RAS superfamily and bindes GTP-b proteins central to the process of vesicle budding. CYTH2 promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Furthermore, CYTH2 promotes the activation of ARF factors through replacement of GDP with GTP. The protein encoded by CYTH2 is a member of the PSCD family. Members of PSCD family appear to mediate the regulation of protein sorting and membrane trafficking. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.
Recombinant Human CYTH2 Protein (rp189363) - SDS-PAGE
3 μg/lane of Recombinant Human CYTH2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 42.9 kDa under reducing conditions and 42.9 kDa under non-reducing conditions.