D15Wsu75e | DeSI-1 | DESI1 | DESI1_HUMAN | Desumoylating isopeptidase 1 | DJ347H13.4 | FAM152B | Family with sequence similarity 152 member B | MGC138384 | PPPDE 2 | PPPDE peptidase domain containing 2 | PPPDE peptidase domain containing protein 2 | PPPDE
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
DESI1 belongs to the DeSI family and contains 1 PPPDE peptidase domain. This protein is a protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins and has isopeptidase but not SUMO-processing activity. DESI1 desumoylates ZBTB46.
Recombinant Human DESI1 Protein (rp189384) - SDS-PAGE 3 μg/lane of Recombinant Human DESI1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 19.9 kDa under reducing conditions and 16.9 & 20.5 kDa under non-reducing conditions. In the non-reducing conditions, the two bands of DESI1 correspond to two conformations respectively (PMID: 22498933).