级别和纯度: 无载体?无载体（Carrier Free）—— 不含添加的载体蛋白/稳定剂。当载体（如 BSA）会干扰偶联或敏感检测时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白，供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。≥90%(SDS-PAGE)expressed in E. coli; 见COA
无载体,His标签,≥90%(SDS-PAGE),expressed in E. coli; 见COA
生化机理
Dual Specificity Phosphatase 22, also known as DUSP22, is a part of the protein-tyrosine phosphatase family which holds 1 tyrosine-protein phosphatase domain. DUSP22 activates the Jnk signaling pathway and dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK). DUSP22 interacts with MAPK1 and MAPK8.
Post-translational: Myristoylation regulates subcellular location, and is necessary for activation of JNK.
Recombinant Human DUSP22 Protein (rp189418) - SDS-PAGE
3 μg/lane of Recombinant Human DUSP22 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the bands at 19.7 kDa under reducing conditions and 19.1 & 37.6 kDa under non-reducing conditions.
DUSP22 is a dual-specificity phosphatase. The catalytic domain of DUSP22 contains a conserved cysteine (Cys) active site, which promotes protein dimer formation through disulfide bond formation (Uniprot ID: Q9NRW4).
危险品化学品经营许可证（带存储）