H2A Histone Family | Member Z | H2AZ | H2A/z | H2A.Z-1 | H2A.z | H2AZ Histone | Histone H2A.Z | H2A Histone Family | Member Z | H2AZ | H2A/z | H2A.Z-1 | H2A.z | H2AZ Histone | Histone H2A.Z
规格或纯度
无载体,≥85%(SDS-PAGE),见COA
生化机理
Histone H2A.Z (H2AFZ) belongs to the histone H2A family. Histones are basic nuclear proteins which are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). H2AFZ is implicated in the formation of constitutive heterochromatin and vital for chromosome segregation during cell division. Moreover, variant Histone H2A, which takes the place of conventional H2A in a subset of nucleosomes. Studies in mice have demonstrated that this particular histone is essential for embryonic development and show that lack of functional histone H2A leads to embryonic lethality.
15.8 kDa, under reducing conditions; 15.8 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 0.4M UREA, 10% Glycerol, pH 8.0
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃(12个月);收货后建议分装,避免反复冻融。
图片
Recombinant Human Histone H2A.Z Protein (rp189469) - SDS-PAGE
3 μg/lane of Recombinant Human Histone H2A.Z Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15.8 kDa under reducing conditions and 15.8 kDa under non-reducing conditions.