C ets 2 protein | ETS2 | ETS2_HUMAN | ETS2IT1 | Oncogene ETS 2 | Oncogene ETS2 | Protein C-ets-2 | v ets avian erythroblastosis virus E2 oncogene homolog 2 | V ets avian erythroblastosis virus E26 oncogene homolog 2 | V ets erythroblastosis virus E26 onco
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
V-Ets Avian Erythroblastosis Virus E26 Oncogene 2 (ETS2) is a transcription factor that regulates genes involved in development and apoptosis. ETS2 is also a protooncogene which takes part in regulation of telomerase. ETS2 protein’s pseudogene is located on the X chromosome.
Post-translational: Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation.
55.4 & 127.4 kDa, under reducing conditions; 53.1 & 114.9 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 0.4M Urea, 10% Glycerol, pH 8.0
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human ETS2 Protein (rp192088) - SDS-PAGE 3 μg/lane of Recombinant Human ETS2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 55.4 & 127.4 kDa under reducing conditions and 53.1 & 114.9 kDa under non-reducing conditions. ETS proteins share an 85-amino acid winged helix-turn-helix DNA-binding domain, which may mediate the formation of dimers (PMID: 25670864).
ZJ25F0319147
危险品化学品经营许可证（带存储）