EXOSC4 is a Non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and takes part in several cellular RNA processing and degradation procedures. In the nucleus, the RNA exosome complex contributes to accurate maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the removal of RNA processing by-products and non-coding 'pervasive' transcripts, like antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing deficiencies, thus controlling or excluding their export to the cytoplasm. Diseases related with EXOSC4 include hepatitis a, and mouth disease.
28.3 & 61.0 & 104.8 kDa, under reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 0.4M Urea, 10% Glycerol, pH 8.0
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human EXOSC4 Protein (rp192092) - SDS-PAGE 3 μg/lane of Recombinant Human EXOSC4 Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 28.3 & 61.0 & 104.8 kDa.
The EXOSC4 Protein is one of the core subunits of the eukaryotic exosome complex, and its function typically relies on multimerization with other core subunits (Uniprot ID: Q9NPD3).
ZJ25F0319516
危险品化学品经营许可证（带存储）