G Antigen 2D | Cancer/Testis Antigen 4.8 | CT4.8 | GAGE-8 | GAGE8 | G Antigen 8.
规格或纯度
无载体, ≥90%(SDS-PAGE), expressed in E. coli; 见COA
生化机理
GAGE2D is a member of the GAGE family, which organized in clustered repeats. In addition, they have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. The first GAGE nomenclature was based on identified mRNA sequences; however the high identity of the GAGE members made it impossible to separate products of paralogous genes from polymorph products. Moreover GAGE2D is not expressed in normal tissues, except in testis; however it is expressed by a large proportion of tumors of various histological origins. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.
Recombinant Human GAGE2D Protein (rp192106) - SDS-PAGE
3 μg/lane of Recombinant Human GAGE2D Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the bands at 25.2 kDa under reducing conditions and 25.1-27.4 kDa under non-reducing conditions.