GIPC 2 | GIPC PDZ domain containing family, member 2 | GIPC2 | GIPC2_HUMAN | Likely ortholog of mouse semaF cytoplasmic domain associated protein 2 | PDZ domain protein GIPC2 | PDZ domain-containing protein GIPC2 | SemaF cytoplasmic domain associated prot
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),See COA
生化机理
GIPC2 is a 315 aa protein which is restricted to the cytoplasm and holds one PDZ domain. GIPC2 is expressed in large quantities in colon and kidney and in small quantities in adult liver. GIPC2 has a vital part in human gastric cancer by control of growth factor signaling or cell adhesion. GIPC PDZ domain containing family member 2, SEMCAP-2, PDZ domain-containing protein GIPC2, semaphorin cytoplasmic domain associated protein 2, semaF cytoplasmic domain associated protein 2, SEMCAP2, FLJ20075.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human GIPC2 Protein (rp192113) - SDS-PAGE 3 μg/lane of Recombinant Human GIPC2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 38.9 kDa under reducing conditions and 36.2 & 39.5 & 87.6 kDa under non-reducing conditions.
GIPC1, GIPC2 and GIPC3 consist of GIPC homology 1 (GH1) domain, PDZ domain and GH2 domain. The regions around the GH1 and GH2 domains of GIPC1 are involved in dimerization and interaction with myosin VI (MYO6), respectively. (PubMed: 23743496)