FLJ25609 | GREPEL 1 | GREPEL1 | GrpE like 1 | GrpE like 1 mitochondrial | GrpE like protein cochaperone | GrpE protein homolog 1 mitochondrial | GrpE protein homolog 1, mitochondrial | GRPE1_HUMAN | GRPEL 1 | Grpel1 | HMGE | Mt GrpE#1 | Mt-GrpE#1
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),见COA
生化机理
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human GRPEL1 Protein (rp192123) - SDS-PAGE 2 μg/lane of Recombinant Human GRPEL1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 25.3 kDa under reducing conditions and 26.3 & 47.5 kDa under non-reducing conditions. GRPEL2 forms dimers through intermolecular disulfide bonds in which Cys87 is the thiol switch. (PubMed: 30098457) GRPEL1 may be similar to GRPEL2.