级别和纯度: 无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。≥90%(SDS-PAGE)expressed in E. coli; 见COA
HLA-DNA | HLA-DZA | HLADZ | HLA class II histocompatibility antigen | DO alpha chain | MHC DN-alpha | MHC DZ alpha | MHC class II antigen DOA | HLA-DOA.
规格或纯度
无载体, His标签, ≥90%(SDS-PAGE), expressed in E. coli; 见COA
生化机理
Major Histocompatibility Complex Class II DO Alpha (HLA-DOA) is a significant modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. HLA-DOA forms a heterodimer along with HLA-DOB. The heterodimer is located in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. HLA-DOA exhibits very little sequence variation, particularly at the protein level.
Recombinant Human HLA-DOA Protein (rp192124) - SDS-PAGE
3 μg/lane of Recombinant Human HLA-DOA Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing the bands at 21.9 & 44.7 kDa under reducing conditions.