HLA class II histocompatibility antigen | DO beta chain | MHC class II antigen DOB | HLA-DOB | Major histocompatibility complex | class II | DO beta | DOB
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),See COA
生化机理
Major Histocompatibility Complex Class II DO Beta (HLA-DOB) is a part of the HLA class II beta chain paralogues. This class II beta chain is a heterodimer which is located in intracellular vesicles and consists of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. HLA-DOB which interacts with the HLA-DM molecule in B-cells is a significant modulator in the HLA class II restricted antigen presentation pathway. Class II molecules are expressed in antigen presenting cells such as B lymphocytes, dendritic cells and macrophages.
表达系统
E. coli
种属
人(Human)
氨基酸
27-224 aa
蛋白标签
N-His
无载体
Yes
无动物源
No
来源
重组表达
预测分子量
23.7 kDa
SDS-PAGE
25.0 kDa, under reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
20mM Tris, 0.4M Urea, 5% Glycerol, pH 8.0
浓度
See COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20℃ for 6 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Human HLA-DOB Protein (rp192125) - SDS-PAGE
3 μg/lane of Recombinant Human HLA-DOB Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing a band at 25.0 kDa.
ZJ25F1129361
危险品化学品经营许可证（带存储）