4933407H12Rik | A type potassium channel modulatory protein 3 | A-type potassium channel modulatory protein 3 | AI413860 | Calsenilin | CSEN | CSEN_HUMAN | DRE antagonist modulator | DRE-antagonist modulator | DREAM | EF hand transcription factor | KCHIP
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),见COA
生化机理
KCNIP3 belongs to a family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. KCNIP family members are small calcium binding proteins containing EF-hand-like domains. KCNIP3 also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Mutations in the presenilin genes are implicated in Alzheimer's disease.
Post-translational: Palmitoylated. Palmitoylation enhances association with the plasma membrane (By similarity). Proteolytically cleaved by caspase-3. Phosphorylation at Ser-63 inhibits cleavage by CASP3.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human KCNIP3 Protein (rp192130) - SDS-PAGE 3 μg/lane of Recombinant Human KCNIP3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.1 kDa.
ZJ25F0218203
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