Arsenic transactivated protein | Arsenic-transactivated protein | ASTP | CHARAC 17 | CHARAC17 | CHRAC 17 | CHRAC-17 | CHRAC17 | Chromatin Accessibility Complex 17 | Chromatin accessibility complex 17 kDa protein | DNA Polymerase Epsilon p17 Subunit | DNA
规格或纯度
无载体,His标签,≥85%(SDS-PAGE),见COA
生化机理
Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Recombinant Human POLE3 Protein (rp192140) - SDS-PAGE 3 μg/lane of Recombinant Human POLE3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 17.1 kDa under reducing conditions and 17.1 & 38.6 kDa under non-reducing conditions. Under high concentrations, POLE3 may undergo non-specific aggregation in vitro; however, this phenomenon is unrelated to its functional activity (PMID: 30217558).