interferon induced transmembrane protein domain containing 1 | BFIC2 | BFIS2 | Dispanin subfamily B member 3 | DSPB3 | Dystonia 10 | DYT10 | EKD1 | FICCA | FLJ25513 | ICCA | IFITMD1 | Infantile convulsions and paroxysmal choreoathetosis | PKC | Proline ri
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca2+-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation.
Store at -20℃ for 12 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Human PRRT2 Protein (rp192154) - SDS-PAGE 2 μg/lane of Recombinant Human PRRT2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 72.6 kDa under reducing conditions and 71.2 & 144.1 kDa under non-reducing conditions. The transmembrane domain of PRRT2 mediates dimerization through hydrophobic interactions under non-reducing conditions (PMID: 27052163).