BPTP 4 | BPTP4 | Dual specificity phosphatase 1 | Hematopoietic protein tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase | HEPTP | LC PTP | LCPTP | LPTP | Protein tyrosine phoshatase non receptor type stress induced | Protein tyrosine pho
规格或纯度
无载体,His标签,≥95%(SDS-PAGE),见COA
生化机理
Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
Post-translational: Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases. Oxidized at active site cysteine. Treatment with pervanadate (vanadate and H2O2) or with antigen enhanced oxidation of active site cysteine (By similarity).
Recombinant Human PTPN7 Protein (rp192177) - SDS-PAGE 3 μg/lane of Recombinant Human PTPN7 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 41.3 kDa under reducing conditions and 41.0 kDa under non-reducing conditions.