Sperm Antigen With Calponin Homology And Coiled-Coil 1 (SPECC1) which is a part of the cytospin-A family takes part in cytokinesis and spindle organization. SPECC1 takes part in actin cytoskeleton organization and microtubule stabilization and therefore necessary for proper cell adhesion and migration.
Recombinant Human SPECC1 Protein (rp192242) - SDS-PAGE
3 μg/lane of Recombinant Human SPECC1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the bands at 32.3 & 40.0 kDa under reducing conditions and 31.5 & 63.3-84.2 kDa under non-reducing conditions.
The SPECC1 protein belongs to the SPIRE protein family. It functions by facilitating actin filament assembly and coordinating the actin and microtubule cytoskeletons. We hypothesize that both bands in the gel image are the target bands (Uniprot: Q5M775).