AlkB homolog 9 | ALKBH9 | Alpha-ketoglutarate-dependent dioxygenase FTO | AW743446 | Fat mass and obesity-associated protein | FATSO, MOUSE, HOMOLOG OF | Fto | FTO_HUMAN | GDFD | KIAA1752 | mKIAA1752 | Protein fatso
规格或纯度
无载体,His标签,≥80%(SDS-PAGE),见COA
生化机理
Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human FTO Protein (rp214414) - SDS-PAGE 3 μg/lane of Recombinant Human FTO Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 57.1 kDa.
ZJ25F0521140
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