Caudal type homeo box 2 | Caudal type homeo box transcription factor 2 | Caudal type homeobox 2 | Caudal type homeobox protein 2 | Caudal type homeobox transcription factor 2 | Caudal-type homeobox protein 2 | CDX 2 | CDX 3 | CDX-3 | Cdx2 | CDX2/AS | CDX2
规格或纯度
无载体,His标签,≥85%(SDS-PAGE),见COA
生化机理
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
Post-translational: Ubiquitinated, leading to its degradation by the proteasome. Phosphorylation at Ser-60 reduces transactivation capacity. Phosphorylation at Ser-283 reduces transactivation capacity and also increases ubiquitin-dependent proteasome degradation.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃保存 6个月；复溶后建议分装，避免反复冻融。
图片
Recombinant Human CDX2 Protein (rp214416) - SDS-PAGE 3 μg/lane of Recombinant Human CDX2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.1 & 47.2 & 50.7 kDa under reducing conditions and 25.3 & 26.6 & 45.7 & 50.9 kDa under non-reducing conditions. CDX2 binds as a dimer to its regulatory element and that dimerization in vitro is dependent on redox potential (PMID: 7935448).
危险品化学品经营许可证（带存储）