HsT1196 | Protein T4-A | SCC | SCCA | SCCA1 | SCCA1SCCA-1 | SCCA-PD | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 | Serpin B3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | Squamous cell carcinoma antigen 1 | T4
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.
42.9 kDa, under reducing conditions; 42.9 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
PBS, 5% Glycerol, 1mM DTT, pH 7.4
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃ 储存12个月；收货后建议分装，避免反复冻融。
图片
Recombinant Human Serpin B3/SSCA1 Protein (rp214464) - SDS-PAGE 3 μg/lane of Recombinant Human Serpin B3/SSCA1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 42.9 kDa.
ZJ25F0623048
危险品化学品经营许可证（带存储）