14-3-3 protein T cell | 14-3-3 protein T-cell | 14-3-3 protein tau | 14-3-3 protein theta | 1433T_HUMAN | IC5 | Protein HS1 | Protein tau | Ywhaq | YWHAQ tyrosine 3 monooxygenase/tryptophan 5-monooxygenase activation protein | theta polypeptide
规格或纯度
无载体,His标签,≥90%(SDS-PAGE),见COA
生化机理
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. Recombinant human YWHAQ was expressed in E.coli and purified by using conventional chromatography techniques.
Post-translational: Ser-232 is probably phosphorylated by CK1.
27.4 kDa, under reducing conditions; 20.0-26.2 & 50.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
PBS, 10% Glycerol, pH 7.4
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃ 存储12个月；收货后建议分装，避免反复冻融。
图片
Recombinant Human 14-3-3 tau/theta Protein (rp220396) - SDS-PAGE 3 μg/lane of Recombinant Human 14-3-3 tau/theta Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 27.4 kDa under reducing conditions and 20.0-26.2 & 50.0 kDa under non-reducing conditions. Members of the 14-3-3 protein family naturally occur in either homodimeric or heterodimeric configurations. The dimerization interface is primarily situated in the N-terminal region and the central α-helical domain (Uniprot ID: P27348).
ZJ25F0926608
危险品化学品经营许可证（带存储）