Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
Post-translational: Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation.Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity).Ubiquitinated on the N-terminus; which is required for proteasomal degradation.Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.
Recombinant Human Myf-3/MyoD Protein (rp220400) - SDS-PAGE 3 μg/lane of Recombinant Human Myf-3/MyoD Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 39.7 kDa.
ZJ25F0826321
危险品化学品经营许可证（带存储）