计算溶液所需的质量、体积或浓度。
SIRT6-IN-3 (compound 8a) is a selective inhibitor of SIRT6 ( IC 50 =7.49 μM). SIRT6-IN-3 inhibits pancreatic ductal adenocarcinoma (PDAC) cells proliferation and induces apoptosis. SIRT6-IN-3 increases the sensitivity of cancer cells to gemcitabine via blocking the DNA damage repair pathway. SIRT6-IN-3 is used in pancreatic cancer research.