SLU-PP-332 is a pan- Estrogen Receptor/ERR agonist with EC 50 values of 98, 230 and 430 nM for ERRα , ERRβ and ERRγ , respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function.