计算溶液所需的质量、体积或浓度。
提供 ≥98% 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
干燥,-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a K i value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Sa
Appearance:Solid
IC50& Target:Ki: 0.32 nM (Angiotensin II receptor)
In Vitro:Saralasin TFA (1 nM, 48 or 72 h) inhibits cell growth in 3T3 and SV3T3 cells. Saralasin TFA (5 μM, 2h) restores I to, fast (Fast-Inactivating Transient Outward K+ Current in Mouse Ventricle) and I K, slow (Slow-Inactivating Transient Outward K+ Curre
In Vivo:Saralasin TFA (intravenous injection, 5-50 μg/kg, a single dose) ameliorates the oxidative stress and tissue injury in cerulein-induced pancreatitis. Saralasin TFA (subcutaneous injection, 10 and 30mg/kg, a single dose) increases serum renin activit
Biological Activity:Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a K i value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Sa