基本描述

别名	光引发剂TMBI \| 2,3,3-三甲基-4,5-苯并-3H-吲哚 \| 1,1,2-三甲基萘并[1,2-d]吡咯
英文别名	1,1,2-trimethyl-[1H]-benz[e]indole \| 1,1,2-trimethyl[1H]-benz[e]indole \| CCG-53010 \| NCGC00256303-01 \| UNII-F56431T911 \| CAS-41532-84-7 \| 1H-Benz(e)indole, 1,1,2-trimethyl- \| SY018592 \| 2,3,3-TRIMETHYL-3H-BENZ(E)INDOLE \| Q-102567 \| 1,1,2-Trimethyl-1H-benz
规格或纯度	≥98%
英文名称	1,1,2-Trimethylbenz[e]indole
储存温度	充氩
运输条件	常规运输
产品介绍	Reactant used for preparation of fluorescent probes for imaging of tumors in vivo, hypoxia-sensitive fluorescent probes for in vivo real-time imaging of acute ischemia and near IR fluorescent probe for imaging integrin receptor expression.

AI解读

关联靶点（人）

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 活性数据)

点击查看靶蛋白信息： PIN1

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 活性数据)

点击查看靶蛋白信息： KMT2A

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)

点击查看靶蛋白信息： CBX1

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 活性数据)

点击查看靶蛋白信息： MEN1

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Rorc Nuclear receptor ROR-gamma (89407 活性数据)

点击查看靶蛋白信息： Rorc

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 活性数据)

点击查看靶蛋白信息： vpr

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504757653
EC号	255-429-8
分子类型	小分子
IUPAC Name	1,1,2-trimethylbenzo[e]indole
INCHI	InChI=1S/C15H15N/c1-10-15(2,3)14-12-7-5-4-6-11(12)8-9-13(14)16-10/h4-9H,1-3H3
InChi Key	WJZSZXCWMATYFX-UHFFFAOYSA-N
Canonical SMILES	CC1=NC2=C(C1(C)C)C3=CC=CC=C3C=C2
Isomeric SMILES	CC1=NC2=C(C1(C)C)C3=CC=CC=C3C=C2
WGK Germany	3
PubChem CID	170530
分子量	209.29
Beilstein号	20(2)294
Reaxy-Rn	153709

化学和物理性质

溶解性	Slightly soluble in water.
敏感性	对空气敏感
熔点	111-117°C
分子量	209.290 g/mol
XLogP3	3.500
氢键供体数Hydrogen Bond Donor Count	0
氢键受体数Hydrogen Bond Acceptor Count	1
可旋转键计数Rotatable Bond Count	0
精确质量Exact Mass	209.12 Da
单同位素质量Monoisotopic Mass	209.12 Da
拓扑极表面积Topological Polar Surface Area	12.400 Å²
重原子数Heavy Atom Count	16
形式电荷Formal Charge	0
复杂度Complexity	315.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	Warning
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany	3
Reaxy-Rn	153709
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到9个结果

批号(Lot Number)	证书类型	日期	货号
E2126170	分析证书	25-03-04	T101089
C1908089	分析证书	22-12-14	T101089
L2207192	分析证书	22-11-17	T101089
L2207202	分析证书	22-11-17	T101089
L2207203	分析证书	22-11-17	T101089
L2207542	分析证书	22-11-17	T101089
L2207586	分析证书	22-11-17	T101089
J2213846	分析证书	22-07-29	T101089
F2204426	分析证书	22-05-24	T101089

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Zhixin Chen, Jiaying Yu, Kai Sun, Jia Song, Lucheng Chen, Yong Jiang, Zhifei Wang. (2023) Rational design of a turn-on near-infrared fluorescence probe for the highly sensitive and selective monitoring of carboxylesterase 2 in living systems. ANALYST, 148 (4): (876-887). [PMID:36661088] [10.1039/D2AN01874H]
2. Baojin Tan, Chao Zhao, Jing Wang, Aliya Tiemuer, Yuanyuan Zhang, Hui Yu, Yi Liu. (2023) Rational design of pH-activated upconversion luminescent nanoprobes for bioimaging of tumor acidic microenvironment and the enhancement of photothermal therapy. Acta Biomaterialia, 155 (554). [PMID:36087865] [10.1016/j.actbio.2022.08.078]
3. Chao Zhao, Fangyuan Zhou, Kai Lu, Shikui Yang, Baojin Tan, Wanlu Sun, Lina Shangguan, Hai-Yan Wang, Yi Liu. (2022) Near-infrared fluorescent probe for in vivo monitoring acetylcholinesterase activity. SENSORS AND ACTUATORS B-CHEMICAL, 360 (131647). [10.1016/j.snb.2022.131647]
4. Junjun Wang, Yize Zhang, Zhi-Peng Yu, Houshi Huang, Lei Chen, Xiaojiao Zhu, Jie Zhang, Lianke Wang, Jianhua Yu, Hongping Zhou. (2021) Diversified photo-energy conversion based on single-molecule FRET to realize enhanced phototheranostics. Materials Chemistry Frontiers, 5 (23): (8229-8237). [10.1039/D1QM01105G]
5. Shikui Yang, Fangyuan Zhou, Xufeng Yao, Wangwang Liu, Wenchao Zhu, Xiaoli Qian, Yi Liu. (2021) A novel near-infrared fluorescent probe to in vivo evaluate the release efficiency of H2S prodrug. SENSORS AND ACTUATORS B-CHEMICAL, 339 (129881). [10.1016/j.snb.2021.129881]
6. Hongyu Li, Ya Liu, Xiaoyi Li, Xiaohua Li, Huimin Ma. (2021) Design, synthesis and application of a dual-functional fluorescent probe for reactive oxygen species and viscosity. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 246 (119059). [PMID:33080516] [10.1016/j.saa.2020.119059]
7. Zhen Ming Dong, Hong Ren, Jia Na Wang, Jian Bin Chao, Yu Wang. (2019) A new colorimetric and ratiometric fluorescent probe for selective recognition of cyanide in aqueous media. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 217 (27). [PMID:30925317] [10.1016/j.saa.2019.03.063]
8. Liyi Fu, Pan Yuan, Zheng Ruan, Le Liu, Tuanwei Li, Lifeng Yan. (2017) Ultra-pH-sensitive polypeptide micelles with large fluorescence off/on ratio in near infrared range. Polymer Chemistry, 8 (6): (1028-1038). [10.1039/C6PY01818A]
9. Liyi Fu, Chunyang Sun, Lifeng Yan. (2015) Galactose Targeted pH-Responsive Copolymer Conjugated with Near Infrared Fluorescence Probe for Imaging of Intelligent Drug Delivery. ACS Applied Materials & Interfaces, 7 (3): (2104–2115). [PMID:25569169] [10.1021/am508291k]
10. Tao Xing, Bin Lai, Lifeng Yan. (2012) Disulfide Cross-Linked Polypeptide Nanogel Conjugated with a Fluorescent Probe as a Potential Image-Guided Drug-Delivery Agent. MACROMOLECULAR CHEMISTRY AND PHYSICS, 214 (5): (578-588). [10.1002/macp.201200568]
11. Tao Xing, Xianzhu Yang, Feng Wang, Bin Lai, Lifeng Yan. (2012) Synthesis of polypeptide conjugated with near infrared fluorescence probe and doxorubicin for pH-responsive and image-guided drug delivery. JOURNAL OF MATERIALS CHEMISTRY, 22 (41): (22290-22300). [10.1039/C2JM35627A]
12. Qiao An,Jing Liu,Meng Yu,Jiaxun Wan,Dian Li,Changchun Wang,Chunying Chen,Jia Guo. (2015-09-15) Multifunctional Magnetic Gd(3+) -Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo.. Small (Weinheim an der Bergstrasse, Germany), 11 ((42)): (5675-5686). [PMID:26366746]

参考文献

1. Song-Jiao Li, Dong-Ye Zhou, Yong-Fei Li, Bin Yang, Juan Ou-Yang, Jia Jie, Juan Liu, Chun-Yan Li,. (2018-07-22) Mitochondria-targeted near-infrared fluorescent probe for the detection of carbon monoxide in vivo.. Talanta, ( 691-700 ). [PMID:30029433]
2. Zhixin Chen, Jiaying Yu, Kai Sun, Jia Song, Lucheng Chen, Yong Jiang, Zhifei Wang. (2023) Rational design of a turn-on near-infrared fluorescence probe for the highly sensitive and selective monitoring of carboxylesterase 2 in living systems. ANALYST, 148 (4): (876-887). [PMID:36661088] [10.1039/D2AN01874H]
3. Baojin Tan, Chao Zhao, Jing Wang, Aliya Tiemuer, Yuanyuan Zhang, Hui Yu, Yi Liu. (2023) Rational design of pH-activated upconversion luminescent nanoprobes for bioimaging of tumor acidic microenvironment and the enhancement of photothermal therapy. Acta Biomaterialia, 155 (554). [PMID:36087865] [10.1016/j.actbio.2022.08.078]
4. Chao Zhao, Fangyuan Zhou, Kai Lu, Shikui Yang, Baojin Tan, Wanlu Sun, Lina Shangguan, Hai-Yan Wang, Yi Liu. (2022) Near-infrared fluorescent probe for in vivo monitoring acetylcholinesterase activity. SENSORS AND ACTUATORS B-CHEMICAL, 360 (131647). [10.1016/j.snb.2022.131647]
5. Junjun Wang, Yize Zhang, Zhi-Peng Yu, Houshi Huang, Lei Chen, Xiaojiao Zhu, Jie Zhang, Lianke Wang, Jianhua Yu, Hongping Zhou. (2021) Diversified photo-energy conversion based on single-molecule FRET to realize enhanced phototheranostics. Materials Chemistry Frontiers, 5 (23): (8229-8237). [10.1039/D1QM01105G]
6. Shikui Yang, Fangyuan Zhou, Xufeng Yao, Wangwang Liu, Wenchao Zhu, Xiaoli Qian, Yi Liu. (2021) A novel near-infrared fluorescent probe to in vivo evaluate the release efficiency of H2S prodrug. SENSORS AND ACTUATORS B-CHEMICAL, 339 (129881). [10.1016/j.snb.2021.129881]
7. Hongyu Li, Ya Liu, Xiaoyi Li, Xiaohua Li, Huimin Ma. (2021) Design, synthesis and application of a dual-functional fluorescent probe for reactive oxygen species and viscosity. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 246 (119059). [PMID:33080516] [10.1016/j.saa.2020.119059]
8. Zhen Ming Dong, Hong Ren, Jia Na Wang, Jian Bin Chao, Yu Wang. (2019) A new colorimetric and ratiometric fluorescent probe for selective recognition of cyanide in aqueous media. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 217 (27). [PMID:30925317] [10.1016/j.saa.2019.03.063]
9. Liyi Fu, Pan Yuan, Zheng Ruan, Le Liu, Tuanwei Li, Lifeng Yan. (2017) Ultra-pH-sensitive polypeptide micelles with large fluorescence off/on ratio in near infrared range. Polymer Chemistry, 8 (6): (1028-1038). [10.1039/C6PY01818A]
10. Liyi Fu, Chunyang Sun, Lifeng Yan. (2015) Galactose Targeted pH-Responsive Copolymer Conjugated with Near Infrared Fluorescence Probe for Imaging of Intelligent Drug Delivery. ACS Applied Materials & Interfaces, 7 (3): (2104–2115). [PMID:25569169] [10.1021/am508291k]
11. Tao Xing, Bin Lai, Lifeng Yan. (2012) Disulfide Cross-Linked Polypeptide Nanogel Conjugated with a Fluorescent Probe as a Potential Image-Guided Drug-Delivery Agent. MACROMOLECULAR CHEMISTRY AND PHYSICS, 214 (5): (578-588). [10.1002/macp.201200568]
12. Tao Xing, Xianzhu Yang, Feng Wang, Bin Lai, Lifeng Yan. (2012) Synthesis of polypeptide conjugated with near infrared fluorescence probe and doxorubicin for pH-responsive and image-guided drug delivery. JOURNAL OF MATERIALS CHEMISTRY, 22 (41): (22290-22300). [10.1039/C2JM35627A]
13. Qiao An,Jing Liu,Meng Yu,Jiaxun Wan,Dian Li,Changchun Wang,Chunying Chen,Jia Guo. (2015-09-15) Multifunctional Magnetic Gd(3+) -Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo.. Small (Weinheim an der Bergstrasse, Germany), 11 ((42)): (5675-5686). [PMID:26366746]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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浓度

x

体积

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分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

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体积 1 (V1)

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浓度 2 (C2)

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

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质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
T101089-5g	5g	现货
T101089-25g	25g	现货
T101089-100g	100g	现货
T101089-500g	500g	期货

1,1,2-三甲基-1H-苯并[e]吲哚

库存信息

库存信息

库存信息

库存信息

基本描述

AI解读

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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此产品的引用文献

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器